Wednesday 26 June Introducing the Zeiss Lattice SIM family, a powerful & versatile end-to-end solution for the Neurosciences (11:30 – 12:00, Open Theatre)
Event organised by Zeiss.This seminar will give an overview of the recently launched Lattice SIM super-resolution instruments, and how the integration within the ZEISS ecosystem enables an end-to-end solution for the neurosciences.The ZEISS Lattice SIM Family enables the researcher to balance the needs in terms of resolution, speed and gentleness according the application: capture entire brain slices rapidly in SIM Apotome mode, follow live vesicle transport using Lattice SIM or dive into the molecular details of synapses using Single Molecule Localization Microscopy (SMLM), all while extracting quantifiable data using ZEISS arivis, going from images to insight.Speaker: Dr. Debora Olivier, Product Management Light Microscopy, ZEISS Research Microscopy Solutions


Art of the mind: Using neuroscience data to create immersive worlds (12:00 – 12:45, Open Theatre)

Event organised by FENS-Kavli Network (FKNE).

 

A picture can speak 1000 experiments. Neuroscience has provided a powerful set of tools to interrogate the mind’s intricate workings, although the human condition is far too complex to be captured by a single empirical dataset. Working in tandem, from the precise to the big picture, neuroscience and art can communicate more than the sum of their individual parts. Modern analytic techniques can generate music, brain data can cause ripples in visual movement, and artificial models can control colour to show the inner workings of the brain through artistic experience. In this event we invite speakers to focus on the big picture, to step back, to connect the dots by thinking, discussing, and providing of examples of how neuroscientific data can become an artistic medium in itself to express complex ideas about the brain.

Speakers: Alejandra Alonso (Netherlands), Joseph Barnby (United Kingdom), Mateuz Ambrozkiewicz (Germany)


INCF launches the Open Neuroscience Award (12:00 – 13:00, Hall D)

Event organised by International Neuroinformatics Coordinating Facility (INCF).


AxL Cleared Tissue LightSheet – Axially Swept Light Sheet Microscopy System for Ultrafast Imaging of Cleared Specimens (13:00 – 13:30, Open Theatre)

Event organised by 3i – Intelligent Imaging Innovations.

 

AxL Cleared Tissue LightSheet (AxL CTLS) is a fully automated macro zoom microscope with high NA apochromatic objectives and dual-sided light sheet illumination for imaging whole organs to small animals. Custom-designed excitation objectives and patented axially swept light sheet microscopy (ASLM) produce an exceptionally thin, long and uniform lightsheet for large-scale high-resolution imaging. ASLM scans the light sheet in its propagation direction using high-speed remote focusing synchronized to the rolling shutter readout of an sCMOS camera at the size of the beam waist. This approach creates an exceptionally thin light sheet across a large field of view resulting in images with improved optical sectioning and signal-to-noise. This scanned sheet features a constant laser intensity across the field of view for an evenly illuminated image. The 0.14NA excitation objective creates a 2μm thin waist for superior axial resolution. AxL CTLS is designed to operate optimally across a range of 1.33 to 1.56 refractive indices ensuring compatibility across all available clearing methods. The large field of view of AxL CTLS enables ultrafast imaging of whole organs to small animals. An entire mouse can be prescanned in less than 60 seconds, imaged in 20 minutes and high resolution ASLM scanned in 9 hours revealing neuronal connectivity.

Speaker: Dr. Daniel von Wangenheim, 3i – Intelligent Imaging Innovations, Germany


FENS CARE – Exploring the necessity of animal experiments (14:15 – 14:45, Open Theatre)

 

The FENS Committee on Animals in Research (CARE) is pleased to focus attention on the critical need of animal experiments in neuroscience research at the FENS Forum 2024. Animal experimentation has been a longstanding practice in scientific research, contributing to numerous advancements in medicine, biology, and other fields. However, the ethical implications and evolving alternative methods have raised questions about the continued necessity of animal experiments. During its open theatre event, CARE members will inform the audience about its work in this area and feature a selection of top entries submitted to the CARE 2024 Writing Competition on animal experiments in brain research.


Tianqiao and Chrissy Chen Institute – Advancing Brain Research (15:00 – 15:30, Open Theatre)
Event organised by The Tianqiao and Chrissy Chen Institute.

 

Dr. Yan Li will introduce the innovative programs of the Tianqiao and Chrissy Chen Institute (TCCI®) which was created in 2016 by Tianqiao Chen and his wife Chrissy Luo, with a $1 billion commitment to help advance brain science. The organization’s vision is to improve the human experience by understanding how our brains perceive, learn, and interact with the world.

She will also present an overview of the Chen Institute’s significant investments in artificial intelligence, which the organization believes has great potential to accelerate the pace of science. In August this year, TCCI®, in coordination with SCIENCE magazine, will launch the Chen Institute and Science Prize for AI Accelerated Research. The prize will be awarded annually to recognize the work of innovative young researchers who apply techniques in Artificial Intelligence (AI), such as Machine Learning, Natural Language Processing, Computer Vision, or Deep Learning, to address basic research questions in the physical or life sciences.

Speaker: Yan Li, Ph.D., Executive Director of Scientific Programs, Tianqiao and Chrissy Chen Institute

Thursday 27 June Femtonics – beyond multiphoton microscopy (11:30 – 12:00, Open Theatre)
Event organised by Femtonics.

  1. Femtonics – Beyond multiphoton microscopy

 

Acousto-optical scanners made a breakthrough in the world of multiphoton microscopy.

Being free from any physically moving parts, AO scanners boosted the temporal resolution beyond 10 µs, and allowed voltage imaging with a frequency mimicking the temporal resolution of electrophysiology.

The same absence of moving parts brought the ultimate flexibility of the imaging patterns with an unprecedented example of “arbitrary plane scanning” – quazi-virtually rotated plane, that permits imaging of coronal, axial, sagittal, and any other tilted sections of the brain without actual rotation of the objective or animal.

The most recent advancement of the high-frequency high-flexibility scanners – is a three-dimensional online motion correction that eliminates relative focus point–sample displacement.

Speaker: Nikita Mikhailov, Femtonics, Budapest

 

  1. Exploring the versatility – Major and minor applications of the FEMTO3D ATLAS microscope

In neuroscience, imaging speed is crucial for capturing as many neurons and dendrites as possible. Faster scanning enables the measurement of more neurons and longer dendritic segments. Speed is especially vital for voltage sensors, which require a higher scanning frequency than conventional two-photon microscopes. With FEMTO3D Atlas, utilizing appropriate voltage sensors, researchers can effectively record voltage signals from a high number of neurons and extensive dendritic segments.

Beyond functional imaging of neurons and dendrites, FEMTO3D Atlas offers a range of additional applications. These include photostimulation, glutamate uncaging, tile imaging, timelapse imaging, blood flow imaging, and more.

Speaker: Mezriczky Zsolt, Femtonics, Budapest


Holistic Approaches to Basic Neuroscience Research (13:00 – 13:30, Open Theatre)
Event organised by Harvard Bioscience.

 

Abstract: Modern neuroscience research benefits from holistic investigation approaches by integrating technologies to study neurological processes at molecular, cellular, and animal levels. Harvard Bioscience (HB) is a global leader in developing solutions to support neuroscience research and drug discovery. HB aims to mitigate laboratory challenges by assisting neuroscientists in a broad spectrum of research needs, furnishing them with diverse, integrated tools that range from in vitro to in vivo.

Speaker: Julio Alvarez, PhD (Biomedical Sciences), Harvard Bioscience, Belgium


Nikon Commercial Solution Multiphoton Microscope (14:15 – 14:45, Open Theatre)

Event organised by Nikon.

 

Dive into thick samples with superior resolution: Discover Nikon Multiphoton microscope AXMP equipped with Nikon Spatial Array Detector (NSPARC)Multiphoton microscopy applications range from in vitro to in vivo where deep imaging, frequently awakened/full organisms are required. Nikon has developed a new multiphoton instrument capable of flexible hardware to meet the increasing demand for deeper imaging in more complex experiment setups. With its vast space under the objective, resonant scanner capability with a large field of view, and 2 new stand options, the Nikon multiphoton microscope AXMP is optimized for gentle deep live cell imaging. Particularly in vivo applications with additional apparatuses for behavioral and neurobiological studies. Moreover, the AXMP can be equipped with an ISM (image Scanning Microscopy) based super-resolution detector: Nikon Spatial Array Detector (NSPARC). This detector allows collecting two-dimensional images on each detector array element achieving a significant improvement in resolution and signal-to-noise ratio. Therefore, combining the NSPARC detector with AXMP closes the gap between different imaging scales within a single system.

Speaker: Sabrina Delattre, European Product Manager Laser Scanning Confocal & MP, The Netherlands


Iconeus One: Pioneering Real-time Whole-Brain Imaging with Functional Ultrasound (15:00 – 15:30, Open Theatre)

Event organised by Iconeus.

 

Discover how Iconeus One, the premier functional ultrasound (fUS) system for neuroscientists, is transforming brain function studies. Based on ultrafast plane-wave sonography, Iconeus One offers exceptional spatial (100 x 100 x 400 µm) and temporal (10 ms) resolution, enabling precise, real-time mapping of hemodynamic changes even in conscious subjects.

This session will highlight the diverse applications of Iconeus One in Neuroscience, including task-induced activation mapping, resting-state functional connectivity, and in vivo dynamic angiography. We’ll showcase how this cutting-edge technology contributes to our understanding of brain function and discuss its future potential with advancements like 3D solutions for whole-brain imaging and connectivity mapping in mice.

Additionally, we will cover Ultrasound Localization Microscopy (ULM), a derivative technique enabled by Iconeus One, offering super-resolution vascular imaging at the micrometer scale. ULM’s ability to visualize functional hyperemia at 6.5 µm will be demonstrated, underscoring its revolutionary impact on brain research.

Join us to learn about the transformative capabilities of Iconeus One and its role in advancing neuroimaging and Neuroscience research.

Speaker: Jeremy Ferrier, PhD, Iconeus, France

Friday 28 June FENS Cast – Live Session (11:30 – 12:00, Open Theatre)

Event organised by GemPharmatech.

 

Join FENSCast host, Richard Roche, for a live session of the official FENS podcast, with EJN editors John Foxe and Yoland Smith


Funny Brains – Science Communication via Comedy (12:00 – 12:45, Open Theatre)

Event organised by FENS Communication Committee.

 

Do you have a knack for comedy, and you always wondered how to use humour to communicate science? Then look no further and register for this networking event, organised by the FENS Communication Committee, where you will have the chance to develop a comedy set based on your favourite neuroscience topic with the guidance of three experts on science communication and comedy.

But that’s not all! You’ll also have the opportunity to perform your comedy set on the Open Theatre stage at the FENS Forum 2024.
Register now here: https://form.jotform.com/241343746826360

This event welcomes all participants of the Forum 2024, and no prior experience with comedy is necessary. Performing the comedy set on the second day is optional and not mandatory for participation. To ensure the best possible experience for all participants, this event is limited to 30 attendees, selected on a first-come, first-served basis.

Please note that this event will take place on two different days:
·      Thursday, 27 June, 18.45 – 20.15: meeting with the trainers to develop a comedy set.
·      Friday, 28 June, 12.00 – 12.45: comedy set performance.

Meet the Mentors:
Rebecca Ellis is an early career researcher based in South Wales. She cares greatly about science communication, especially through creative methods such as poetry, comedy, art, and improv. She runs the Instagram account @Neuro_Divers, discussing all things neurodiversity.

John Butler is a Lecturer in the TU Dublin, Ireland. His research focuses on multisensory integration. Over the last decade he has organised, hosted and presented at numerous science communication events: Maths Week, Science Week and Pint of Science.

Michele Marini is a Biotechnologist and a stand-up comedian. He is a marketing and communication expert in the life biotherapeutics field and runs stand-up comedy shows in Italian and English in Belgium and Italy. He hosts live and online events dedicated to science like Pint of Science and Couch of Science.

 

Speakers: John Butler (Ireland, Rebecca Ellis (United Kingdom), Michele Marini (Belgium)


Mindfulness Session: Focus On The Breath (13:00 – 13:30, Open Theatre)

 

During our sessions, we’ll explore various yogic breathing techniques aimed at relaxing the body and laying a solid groundwork for meditation. Yogic meditation techniques primarily emphasize focus. Regardless of the distractions around us, we train our attention to return continually to a focal point, which could be our breath, a specific part of our body, a visualization, or a sound.

 

Guided by Giulia Tamiazzo – Certified Yoga & Meditation Teacher Mag. Giulia Tamiazzo MA is owner of the yoga and meditation studio RE:TREAT in the heart of Vienna and is certified yoga and meditation instructor. She has been teaching for over ten years and will be introducing yogic meditation practices.


Unveiling GemPharmatech’s Neurological Mouse Models: Advancing Research and Therapeutic Development (14:15 – 14:45, Open Theatre)

Event organised by GemPharmatech.

 

Embark on a journey into GemPharmatech’s neurological mouse model resources, where an unwavering commitment drives the understanding and treatment of neurological diseases in academia and the pharmaceutical industry. Our suite of meticulously crafted mouse models, including simulations of Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), Huntington’s disease (HD), and beyond, serves as indispensable tools for deepening insights into disease mechanisms and evaluating therapeutic interventions. Additionally, inducible disease models further support drug discovery efforts across diverse areas such as pain, PD, and depression. Furthermore, our library also includes knockout (KO) and conditional KO (cKO) mice, aiming to encompass the ~23,000 protein-coding genes in the mouse genome. In addition to our extensive mouse model library, we provide up to 50 Cre strains related to the nervous system, enabling spatiotemporally regulated gene expression. Join us in exploring the transformative potential of our models, driving scientific breakthroughs, and fostering collaborative efforts in academia and the pharmaceutical industry.

Speaker: Dr. Rui FENG, GemPharmatech Co.,Ltd., China

Saturday 29 June Science Literacy: How the Neuroscience Community Can Contribute (11:30 – 12:30, Open Theatre)

Event organised by FENS-KAVLI Network of Excellence (FKNE).

 

Although recent efforts across Europe have aimed to foster a dialogue between science and society, for many individuals, science remains distant from their daily lives. This gap has been exacerbated by recent environmental and public health crises, increasing misinformation and distrust. Consequently, policy misalignments, with decisions not consistently grounded in scientific evidence, may result. To address these challenges, multifaceted efforts aim to bridge this divide: Scientific communities have intensified their science outreach. By extending into educational settings, an early foundation for scientific literacy may be reached. Funders increasingly support initiatives that aim to improve dialogue between scientists, society, and policymakers. At the heart of all these efforts is the drive to enhance public science literacy. Science literacy refers to the understanding of science and the scientific process, including the framework by which an individual’s decision making is guided by research, facts, and knowledge instead of mere opinions or hearsay. Still, the question remains: What is the most effective path to achieving an increase in science literacy in the general population? The Science Literacy Session, organized by the FENS-KAVLI Network of Excellence, aims to explore these strategies by bringing several relevant stakeholders to a moderated panel. By integrating the perspectives of science communication experts, program initiators, funders, and neuroscientists, we aim to take a first step to formulating a joint mission statement that highlights promising paths toward an increase in public science literacy.

 

Speakers: Julia Serong (Germany), Emma Yhnell (United Kingdom), Christian Bertsch (Austria), Selahattin Danisman (Germany), Sabine Gysi (Switzerland)